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Monday, 09/14/2020 8:17:19 AM

Monday, September 14, 2020 8:17:19 AM

Post# of 687273
Breast Cancer - Off-Label - 2000-2007

Results
13,347 women were treated with 16,127 regimens (12% of women switched to a new regimen during followup).

Sixty-four percent (10,391) of regimens were off-label/supported,

25% (3,987) were on-label and 11% (1,749) were off-label/unsupported. Drugs never supported for breast cancer accounted for 19% of off-label/unsupported use and 1% of total use. Hospitalization/ER admission occurred in 32% of off-label/unsupported regimens, compared to 27% of off-label/supported and 25% of on-label regimens (p<.0001).


Prevalence and safety of off-label use of chemotherapeutic agents in older breast cancer patients: estimates from SEER-Medicare data
2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827612/
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