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Friday, September 11, 2020 6:06:25 PM
Try to understand what a “cold tumor” is and why PDL1 blockers would not make a tumor “hot”, and also why a vaccine in combination with a PDL1 blocker later in the lecture would be so helpful, as well as why contrary to his point about GBM having so few targets, most immune therapies for GBM in the past have only targets single or just a few targets, allowing the tumors to evolve away and why having a therapy that targets all of the patient‘s specific antigens is superior.
That is a very general and not specific to DCVax-L presentation. You’ll need to do some more homework. Don’t invest until you do it though. Never invest in anything you don’t understand and I’m which you are not confident. You’ll need to convince yourself that it’s worth the risk.
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