NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

1st unblinding (of statisticians) ultimately for regulator consumption.

2nd unblinding (of Company, SAB and Steering Comm.) ultimately for Journal Preparation and public consumption (aka: SNO). (More than five years from last surgery)

3rd unblinding (of actual patients) ultimately for posterity/future patient info, Journal follow up. (More than five years from last enrollment)

IMO

Again, the company themselves have made a big deal of the fact that they won’t be unblinded until multiple weeks after the statisticians. Will you be unblinded when you Get TLD? No. Will patients be unblinded at TLD? Probably not. There are different levels of unblinding. There is a reason why some trials start with quadruple blinding.

Note: Novocure’s Optune trial was NEVER blinded.