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Thursday, July 30, 2020 9:04:12 AM
Do you not think Leronlimab is going to show superior efficacy compared to the placebo arm? It would not surprise me if Leronlimab arm has zero to very few deaths.
With a 2:1 ratio of drug vs placebo let’s take a guess at the current 150 patients enrolled.
50 placebo - 10 deaths
100 Leronlimab - 2 deaths
That would equate to 1 death for every 10 deaths in the placebo arm.
Is that enough statistical relevance to halt the placebo arm or possibly halt the trial and grant emergency approval?
I personally don’t think those numbers are far reaching when one considers Leronlimab’s efficacy for severe patients up to this point. Just rewatch the Patterson Ted Talk and think it through again.
A17, I know you play the devils advocate w everything. Throw the devil at the S2C trial - he’s going to find a different place to play. As Lalezari has stated many times this is a home run.
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