Cytodyn Inc (CYDY)

[bobshmob]

These are great wuestions, gfp927z, and I guess we'll find out the answers soon. But we can do a little pre-game prognosticating right now.

how long does it take for Covid to progress from mild/mod to severe?

Not long at all. The bigger concern for me is how long is the recovery time? Most patients--both placebo and leronlimab--will recover within 14 days. Will there be enough placebo patients either getting worse (expect 15% or so) or not fully recovering (another 35% or so) to make a difference?

what percentage of mild/mod Covid patients typically worsen and move into the severe stage?

Don't need very many severe cases to move the needle quite a bit. If 4 or 5 of 28 placebo patients move to severe, it's game over. Leronlimab wins. But they don't need to move all the way to severe to move the needle toward leronlimab ya' just need to not move to recovery as fast.

But, really, this is all speculation. It looks like NP may give the score tomorrow, and BP will follow up with post-game analysis next week.

s/c? I keep looking at all the deaths in the critical Montefieore cases and the updated estimates of mortality for severe/critical cases (much lower than previously thought), so I'm just not sure.

A wild guess:
leronlimab will look good for m/m
lenlizumab will look good for s/c (leronlimab will too!)

FDA badly wants a win, and it'll get two with these mabs from these David small pharma OTCs knocking off the Gilead Goliath. [Of course, remdesivir isn't going anywhere because Fauci likes his cocktailsw his Gilead buddies, and the idea of NIAID moving so darn fast to bring us this expensive, dangerous, life-saving placebo]