Anavex Life Sciences Corp (AVXL)

[sokol]

Supposition, but perhaps change the gut microbiome is associated with increased mitochondrial complex I activity. According to the recent Seeking Alpha article, "A2-73 ... increased mitochondrial complex I activity, which is dysfunctional in PD neurons."

https://seekingalpha.com/article/4357368-anavex-is-likely-to-report-positive-parkinsons-disease-trial-results-for-a2minus-73

A new study found that exercise -- and in particular high-intensity interval training in aerobic exercises such as biking and walking -- caused cells to make more proteins for their energy-producing mitochondria and their protein-building ribosomes, effectively stopping aging at the cellular level.

https://www.sciencedaily.com/releases/2017/03/170307155214.htm

Recent studies suggest that exercise has a number of benefits for the gut microbiota. It is linked to increases in the number of beneficial microbial species and enriching microbial diversity as well as enhanced short-chain fatty acid synthesis and carbohydrate metabolism.

https://atlasbiomed.com/blog/how-does-exercise-affect-gut-microbiome/

I have not found much more about this and it may not be very helpful, but see this:

Host mitochondria influence gut microbiome diversity: A role for ROS

https://stke.sciencemag.org/content/12/588/eaaw3159