Therapeutic Solutions International Inc (TSOI)

[sharky]

StemVacs™ is a cell-based drug comprised of dendritic cells activated in a proprietary manner which when administered stimulates a type of immune system cell termed "natural killer" or NK cells. Numerous studies have shown that NK cells are involved in protecting the body from cancer and from viruses. The FDA has allowed for clinical trials of COVID-19 patients using an NK cell-based drug termed CYNK-001 [1].

Immune therapy of COVID-19 patients has been considered by some as a double-edged sword. On the one hand, it is desirable to augment immune responses to control the virus, on the other hand, excessive immunity is known to lead to acute respiratory distress syndrome (ARDS), which is a major cause of death. The current animal data sought to replicate the lungs of patients suffering from ARDS by treating mice with a potent activator of the innate immune system molecule TLR4. To the surprise of Company scientist's administration of StemVacs™ actually reduced the lung inflammation.


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