Horseb4CarT Friday, 07/03/20 02:15:52 PM Re: biosectinvestor post# 293474 Post # of 299084 Adding my 2 cents, I think it’s conjecture until combo trial results are obtained however it sounds like hope from the healthcare community that combo treatments might do better than the individual treatments. Merck is going to try with the combo trial that is supposed to happen, which I think is dcvax + CI, presumably attacking a person’s cancer with dcvax targeting the tumor targets while the checkpoint inhibitor hindering the cancer’s ability to deceive the immune system to look friendly rather than hostile to avoid immune system attack. Again I’m not an expert or practitioner so I could be off base. The Car-T treatments appear to have some risk of bad reactions and morbidity for some patients according to what I’ve read, if I interpreted correctly. Maybe a combo might lessen the risk, maybe not, and maybe be more effective. Regarding melanoma treatments I think I remember a trial out of Mt Sinai in NYC that involved an immunotherapy approach, but the news was from 1-2 years ago and I’m foggy as to whether it was melanoma. I know two people who have melanoma and appear to be living with ongoing checkups and surgeries/treatments, whereas i don’t think such was the case in the past. If I find something I’ll post it.