Anavex Life Sciences Corp (AVXL)

[bas2020]

Simply put, the placebo effect is psychological, whereas the gene variant effect is biological, whether it be beneficial or detrimental. Thus, the placebo effect is temporary, lasting from a few days to several weeks; whereas the gene variant effect is sustained. Placebo effects are independent of any gene variant effects, meaning they may or may not coexist with a given patient.

Many suspect that patients with moderately detrimental gene variants may experience improvements in therapeutic response at higher dosages, up to the individual's MTD.