NorthWest Biotherapeutics Inc (NWBO)

[longfellow95]

Just to be devil's advocate, Senti; what are those steps?

I suppose you could try switching the computer off at the mains before rebooting and trying again a few times, if you don't like the first readout.
The data is what the data is, and has to be applied to the statistical analysis, as described in the SAP, which had to have been finalised before unblind.

Seriously, I know what LP said, but I really don't know what these other time-consuming steps (while the data remains solely with the Stats) actually are. Yes, you would want to run maybe hundreds of subtests that would enable you to identify and quantify positive outcomes in sub-populations (such as older trial subjects, who have done particularly well in this trial, compared to expectation)
I don't see why there is any imperative for the company to remain blinded, while the unblinded data is with the Stats. Obviously company folk won't be able to calculate p values and such like, but if I was in LP's shoes, I would want to give myself the maximum time to consider the implications of the data, and then to reach a resolve as to how the company will go forward with the data, what will go in a topline announcement, how it will be presented, and how the company will move forward beyond that.

I can see an ongoing dialogue with the Stats as being useful (for example, around the relative statistical strength of meth v unmeth data), but I don't get the 'first them, before us' approach.

Maybe it's just normal protocol for the Stats to get first look.