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Tuesday, May 19, 2020 8:37:34 AM
I think I was first to refer to them.
You would hope that physicians around the world could report their experiences anonymously, without fear or favor.
But I wonder if that is truly the case. Perhaps less than it was a month ago.
And Italy and Spain only started widespread use of HC when their deathrate was out of control.
Its use coincides with the subsequent decline in mortality!
And the point about HC is that it is most effective for mild to moderate cases, where viral load is likely lower.
Once a patient gets to the ARD stage, HC won't help.
That's when you need to use Tocilizumab!
Which Sermo also report on, but its use gets virtually no mention in any media anywhere in the world. Why?
I have no doubt it is saving lives of critically ill patients, where it is in use.
The poorer, less developed parts of the world, or those outside the Western world are largely relying on HC, because they haven't got anything else.
It is in wide usage in India. But then you get crazy articles criticising India for using it, and at the same time criticising India for restricting its export.
UAE are importing it from India, I know that much.
And India are also using it as a preventative for health workers and other other hig risk groups.
Pakistan is using it, and has enough stock to be exporting to many other countries:-
the government had allowed export of one million tablets to Saudi Arabia, five million to the UK, one million to the US, half a million each to Turkey and Italy, 300,000 to Qatar, and 700,000 to Kazakhstan.
Though God knows why the UK is importing it, if it won't sanction its use.
I know that its use in France and the UK is low. And according to UK guidance to physicians, it's not supposed to be used at all.
But it would seem a minority of physicians are still prepared to use it off-label.
And how does Sermo actually calculate percentage use of HC per country anyway? I know of no official data.
France and the UK clearly have very high cases to deaths, which is probably a true reflection of minimal use of approved re-purposed drugs such as HC and Tocilizumab. But it could also reflect just low testing, compared to actual undiagnosed (asymptomatic or minimal symptoms) at large in the country.
I would also question whether HC use in the US is really as low as 17%. It has official sanction for use after all. Maybe Iwasadiver can give a view on that.
I can't prove my assertion admittedly, but that's the problem. There is a veil of information regarding HC use, as well as a wave of negative press in Western countries (which I am extremely cynical about).
A Sermo reporting physician stated:-
An anonymous Pediatrician on Sermo commented, “I took Chloroquine for a year in southeast Asia to prevent malaria. So did another 3,000,000+ soldiers. I suffered no ill effects and this letter is proof of no death. The dead do not have time for the FDA’s randomized clinical trials. Just ask them.”
Yet upbeat Remdesivir stories are everywhere.
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