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Re: HinduKush post# 269634

Monday, 04/27/2020 3:42:01 PM

Monday, April 27, 2020 3:42:01 PM

Post# of 424038
WRONG. Vascepa had a very small increase in Afib seen. Most of it was related to people who already had a Hx Afib and just went back into it which we see all the time with Afib pts. After you take those people out it was a fraction of an increase in Afib in those without a hx. HCQ and Zithromax temporarily causing an increase in a prolonged QT which is what has been shown so far is very close to being clinically insignificant. Close bc it’s insignificant unless it leads to part 2 which is an arrhythmia. The news keeps talking of possibility of leading to cardiac events but that’s not enough. It has the POTENTIAL to increase the chance of Afib (very very very small chance). We give other meds that prolong the QT all the time for colitis (zofran and cipro together ) and rarely ever see it cause Afib or torsades a far worse deadly arrhythmia. It’s a theoretical risk that can happen and will happen on a freak event but you are talking about extraordinarily rare events. To even consider not giving Vascepa with HCQ and z pack would be mal practice. Vascepa doesn’t prolong the QTC. It’s two diff mechanisms.
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