Amarin Corp Plc (AMRN)

[jessellivermore]

I've read Mori..

Mori was not a Japanese study...but was published in a Nutrition Journal.

It involved 59 patients 56 finished the trial..there were three groups of slightly overweight males.. Trial was double blinded

A) Olive Oil

B) EPA 1.8 gms/day

C) DHA..1.8 gms...


https://academic.oup.com/ajcn/article/71/5/1085/4729166

Results: Fifty-six men aged 48.8 ± 1.1 y completed the study. Relative to those in the olive oil group, triacylglycerols fell by 0.45 ± 0.15 mmol/L (˜20%; P = 0.003) in the DHA group and by 0.37 ± 0.14 mmol/L (˜18%; P = 0.012) in the EPA group. Neither EPA nor DHA had any effect on total cholesterol. LDL, HDL, and HDL2 cholesterol were not affected significantly by EPA, but HDL3 cholesterol decreased significantly (6.7%; P = 0.032). Although HDL cholesterol was not significantly increased by DHA (3.1%), HDL2 cholesterol increased by ˜29% (P = 0.004). DHA increased LDL cholesterol by 8% (P = 0.019). Adjusted LDL particle size increased by 0.25 ± 0.08 nm (P = 0.002) with DHA but not with EPA. EPA supplementation increased plasma and platelet phospholipid EPA but reduced DHA. DHA supplementation increased DHA and EPA in plasma and platelet phospholipids. Both EPA and DHA increased fasting insulin significantly. EPA, but not DHA, tended to increase fasting glucose, but not significantly so.

This is a study published in a Nutrition Journal and not a peer reviewed CVD study...The results were so-so...EPA lowered Trigs to a slightly lesser degree than DHA...EPA lowered HDL and DHA raised HDL2 by 29% while EPA lowered HDL3 significantly (6.7%) Higher HDL would be considered beneficial by many at the time of this study. Interestingly although DHA increased LDL (bad) DHA did increase the LDL-C particle size (which is considered beneficial...While EPA did not increase LDL-C it did not increase LDL-C particle size...So the effect on LDL-C could be considered a tie..This non peer reviewed nutrition study in no way says anything concrete about predicting that EPA would be superior to DHA..Or provides any evidence to support obviousness of EPA in lowering CVD event risk..or even the Marine trial as this would require an apples to oranges comparison...

This judge is either corrupt or lacks the mental skills which a judge needs....

":>) JL