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Re: north40000 post# 256544

Thursday, 03/26/2020 4:55:34 PM

Thursday, March 26, 2020 4:55:34 PM

Post# of 426436
There has been some research in this area. Should be addressed with further trials.

EPA-Lung Tissue

Conclusion

EPA-preconditioned AD-MSCs increased secretion of pro-resolution and anti-inflammatory mediators (RvD1, PGE2, IL-10, and TGF-ß) by these cells. In CLP-induced sepsis, this was associated with further reductions in lung and distal organ damage, thus resulting in greater improvements in clinical score and higher survival rate, compared to therapy with nonpreconditioned AD-MSCs. This may be a promising therapeutic approach to improve outcome in septic patients.
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