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Re: KMBJN post# 142128

Tuesday, 03/24/2020 11:58:06 AM

Tuesday, March 24, 2020 11:58:06 AM

Post# of 146240
Interesting that others are trying to make similar artificial viral traps against SARS-CoV-2, using ACE2 receptor as a "decoy" or mimic, just like what Diwan/Theracour/NNVC is doing:

https://finance.yahoo.com/news/sorrento-develops-sti-4398-covidtrap-110010134.html

STI-4398 is a proprietary ACE2 (angiotensin-converting enzyme 2)-Fc fusion protein (COVIDTRAP). The STI-4398 protein binds to the S1 domain of the spike protein, which is expected to block the spike protein of the SARS-CoV-2 virus to bind the ACE2 receptors present on the target respiratory epithelial cells. Without the ability to penetrate target cells, the SARS-CoV-2 virus cannot replicate and spread itself. By interfering with the viral infection cycle, STI-4398 might be the most effective way to prevent an infection to progress to a fully advanced COVID-19 disease. This approach could be ideal in generating passive immunity and shielding at-risk populations, including healthcare providers, the elderly population or patients with compromised immune systems, from developing the COVID-19 disease after viral exposure.



Hard to say if their COVIDTRAP will destroy the virus or not.
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