NorthWest Biotherapeutics Inc (NWBO)

[Umibe5690]

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Then how do you explain the classification in the intro to the iHub message board which classifies pro neural as M+ and MES as M-? Is that abstract wrong???

Further, isn't M+ longer lived? Isn't this due to interference with the cellular repair mechanism thus conferring longer survival? MES was considered highly aggressive in earlier studies by Liau and Prins, however due to its immunogenicity(more residual T-cells and less immunosuppressive micro-tumour environment), DC VAX L showed impressive results. What percent of MES is M+? What other molecular sub-groups are M+? Pro neural? If so, then how do you account for Prins' statement that the vaccine had little to no effect upon pro neural? He mentioned nothing about its association with M+ or whether it was G-cimp, etc.

BTW, the above referenced classification abstract is rather recent---February, 2018. I have raised these issues previously. Best wishes