Saturday, February 22, 2020 12:37:40 PM
I’ve been thinking about all the quotes that I’ve read from Merck executives over the past couple of years and the type of assets Merck was interested in acquiring, and I’m sure that if this trial has positive topline, and Northwest Bio presents very compelling full data at ASCO, that Merck (and other BP) will be extremely interested. I’m not so sure how interested Northwest Bio is in partnering at this point though. I would sure like to be a fly on the wall during those discussions.
I think that manufacturing in the U.S. is ready, and nearly ready in the UK, and Linda is prepared to file a BLA, NDS, and MAA, and take DCVax to market on their own, and is not looking to partner DCVax for glioblastoma. From Linda’s point of view, she could use BP’s money and regulatory expertise, but it may not be worth cutting them in because Big Pharma has little cell manufacturing capabilities, and DCVax would still likely be manufactured by Cognate and Advent who are familiar with, and have automated and industrialized the process for commercial manufacturing. In addition, BP’s large sales and distribution infrastructure is not really needed for a personalized treatment that will initially be distributed through the few hundred neuro-oncologists and medical centers that participated in the trial and are familiar with DCVax, which could easily be handled by a sales force of under 50, perhaps even 25. With an approvable cancer treatment and credibility reestablished, and an uplisting on Nasdaq, I think Northwest Bio will be able to attract favorable financing, which would give Linda considerable leverage if negotiations become serious later this year.
I have wondered why Northwest Bio has not started any of the clinical trials that they have talked about last year. Is it really because they don’t have the financial resources or perhaps another reason? If DCVax proves effective for glioblastoma, I have to believe that Merck would like to run hundreds of trials with DCVax, both as a single agent in multiple indications, and in combination with Keytruda, and they may not have the patience that we investors have had with Northwest Bio’s clinical development plan or pace. From Ken Frazier’s most recent public comments at the JPM Conference, it seems Merck may be able to justify paying a high price for just such a platform technology. Should be interesting.
Recent NWBO News
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 09/03/2024 08:01:40 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/13/2024 08:01:24 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/09/2024 09:06:07 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/08/2024 08:30:09 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 08/02/2024 02:42:28 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 07/30/2024 11:49:38 PM
- Biophma Announces Exclusive In License for Dendritic Cell Technology, Sending Shares Higher • AllPennyStocks.com • 06/17/2024 04:40:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 06/04/2024 09:11:16 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 06/03/2024 09:22:55 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 05/22/2024 08:13:36 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/10/2024 09:04:57 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/01/2024 10:04:38 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 12/02/2023 01:31:35 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/16/2023 10:11:54 PM
- Epazz, Inc. (OTC Pink: EPAZ) ZenaDrone Demonstration to Defense Departments of UAE and Saudi Arabia • InvestorsHub NewsWire • 11/15/2023 12:19:31 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/09/2023 09:30:39 PM
- Epazz, Inc. (OTC Pink: EPAZ) US Navy Collaboration ZenaDrone 1000 • InvestorsHub NewsWire • 11/09/2023 01:00:34 PM
- Epazz, Inc. (OTC Pink: EPAZ) US Navy Collaboration ZenaDrone 1000 Extreme Weather Demo • InvestorsHub NewsWire • 11/07/2023 12:29:43 PM
VHAI - Vocodia Partners with Leading Political Super PACs to Revolutionize Fundraising Efforts • VHAI • Sep 19, 2024 11:48 AM
Dear Cashmere Group Holding Co. AKA Swifty Global Signs Binding Letter of Intent to be Acquired by Signing Day Sports • DRCR • Sep 19, 2024 10:26 AM
HealthLynked Launches Virtual Urgent Care Through Partnership with Lyric Health. • HLYK • Sep 19, 2024 8:00 AM
Element79 Gold Corp. Appoints Kevin Arias as Advisor to the Board of Directors, Strengthening Strategic Leadership • ELMGF • Sep 18, 2024 10:29 AM
Mawson Finland Limited Further Expands the Known Mineralized Zones at Rajapalot: Palokas step-out drills 7 metres @ 9.1 g/t gold & 706 ppm cobalt • MFL • Sep 17, 2024 9:02 AM
PickleJar Announces Integration With OptCulture to Deliver Holistic Fan Experiences at Venue Point of Sale • PKLE • Sep 17, 2024 8:00 AM