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Re: flipper44 post# 262488

Friday, 01/31/2020 12:44:23 PM

Friday, January 31, 2020 12:44:23 PM

Post# of 704263
Umbibe states that Les indicated that he agreed with Uribe's statement that "If separation occurs then that is good for the trial depending upon the amount of curve separation. If there is none, it is good for patients, shows powerful efficacy in recurrent GBM even without second resection. So that would be good."

So Les is agreeing with that statement. What he followed with is that IF the trial is not stat sig, or there is not enough separation between the two, there are " forces that will strongly support the letter of the trial parameters and throw the baby out with the bathwater."

In point of fact, do you yourself not actually agree with that statement accorded to Les by Umibe? Do you not think there are forces comprised of some people, be they doctors who give opinions on adcoms, or media analysts and bloggers, and possibly a few or more people in the actual regulator agency offices, etc., etc.?

Perhaps Les is worried more about that possibility than Umibe is, or you for that matter. But nevertheless, it is something to think on, and as one of the heads of the company, it behooves him (and the company) to consider this possibility and to take steps to best protect the trial from such forces.
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