NorthWest Biotherapeutics Inc (NWBO)

[Barunuuk]

What mystery mode? It is explained in the article. It is just mathematics and statistics. We understand the ratio, it’s 2:1 treated to placebo.

So if you know the SOC graph you can then adjust the data to see what would be needed for the same blinded results.

Take the equation a + 2b = c. If you now c (blinded data) and you can plug in a from other SOC trials, then you can solve for b.

For the unsuccessful model it is trial and error, as we are saying the mOS of a is < 2 months. So I keep solving for both until I get the same blinded results. Hope that helps.