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Thursday, January 23, 2020 2:43:43 AM
There is a prestigious SAB and at least 69 supporters. Are Drs. LL and Ashkans in on the scam?
Did LP/LG pull the wool over some pretty smart people including Judges? What did the SEC find after all these years?
I suppose anything is possible and they are insane with greed. However, the probability is certainly nil. It makes no sense. I think the science is solid and legitimate. Apparently, some very smart professionals think so too.
It may be entertaining to engage in statistical masturbation on the MB, but there is no one on this board who is credible and a professional statistician--at least as far as I am aware. I am certain that LP/LG have some PhDs and very experienced statisticians who do this for a living and who they pay very well. NWBO has been extremely careful when dealing with the regulators. It is relatively easy for an agency to issue the dreaded CRL letter unless the data and the way it is presented is undeniable. Since they have orphan status, I am certain that NWBO and the RAs have had continuing discussions and "guidance".
Furthermore, I don't agree that NCVR is a scam either. Obviously, the data is not as rich as data from the DC VAX L trial. The bar for Optune approval was lower considering the intractability of the disease and the fact that there was no significant progress since 2005. Better surgical techniques/SOC may have added some little time. Patients deserve a viable alternative to a helmet and the blinded results from the DC VAX L trial look at least as good as the Optune Tx. Unless there is something that is terribly out of kilter at this stage, I think it is fair to say that the odds favour approval and hopefully relatively expeditiously.
Scams? I think that is nonsense. JMHO.
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