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Re: Investor2014 post# 231124

Sunday, 01/19/2020 9:32:08 AM

Sunday, January 19, 2020 9:32:08 AM

Post# of 458546
Thanks, yes saw this post. You’re deductive reasoning and speculative dot connecting are on point. I will say I am not 100% convinced because I personally think the reasoning for waiting so long before starting the OLE still begs many questions. One would think the OLE design would be nailed down many months in advance.

Additionally, you say:

“At the same time Anavex may also have decided they need to go all the way to 50mg or MTD in the PDD OLE. “

If this is correct and Anavex realized in the OLE they needed titrate up to 50mg, would it be a stretch to say the 10 & 20 mg doses in the main trial were not proving efficacious?
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