NorthWest Biotherapeutics Inc (NWBO)

[hyperopia]

Thanks for the post longfellow

Well what does 'Operationally Practical for Commercialization' actually mean?

I think Northwest Bio is implying that DCVax can eventually be produced at a commercially cost effective price as opposed to Dendreon or the current CAR-T treatments that are cost prohibitive and have had a lot of pushback from healthcare insurers, and not everyone can afford. Linda and others associated with the company have been emphatic about bringing the costs of production down so that everyone can afford the DCVax treatment.

It is clear that manual production is time consuming and expensive (the largest cost is probably the manual labor) which is why they state DCVax is "amenable to automation” to indicate that both of these issues of cost and time can be overcome through automation. Again, they likely wanted to differentiate DCVax from treatments which can only be manually processed. And yes automation requires more capital expenditures, which is why the manual process was used during the trial.

And I agree that 99% is likely the goal, but Gilead had been producing Yescarta treatments97% to specification, and seems proud to announce this. (probably to troll Novartis)

https://www.biopharma-reporter.com/Article/2019/04/01/Gilead-produces-97-on-spec-Yescarta