Cassava Sciences Inc (SAVA)

[Pineapple1]

Sorry on my phone so it's hard to do citations. If you go to the PR on CTAD in Dec they have a link to the downloadable link. There I read over the inclusuonary criteria, where the age range is 55 to 85 and MMSE scoring range at baseline. They state in the presentation that they did not use MMSE (which is a commonly used Alzheimer's test) mini mental stae exam score as a primary indicator for their trial. The FDA has stated that cognition is a must before approval, so you would presume that the company would design a test that not only looks at biomarker reduction but also a stabilization of cognitive ability, or stability in the other commonly used test Activities of Daily living (ADL). This poor design shows how little they know about their drug and that they are not testing to a high standard. If i was advising someone about this company i would stear clear and look for a company with better science.