Amarin Corp Plc (AMRN)

[Jeffkad]

As I said to sts66, I do think docs will prescribe wider than several of the restrictions, but the one restriction I think will stick is statin use. I could see DM+statin and forget the extra risk factors, or statin user plus high trigs and some risk factors but no CVD. I just don’t see dropping statin use as qualifier. The entire study is based on this underpinning drug. We all get the greater benefit as we are V diehards, but I do not see the average doc prescribing without underlying statin use. Why would they? The R-It results must presume a complimentary effect based on the concomitant use of statins and V. As I said, if a doc digs into the actual study, he/she will find nothing that supports use without statin. Unless the doc is a diehard like us here, or believes in the Evaporate results justifying standalone anti-inflammatory benefits, there is no justification.

I think we’ve just about beaten this horse to death lol, so we’ll just have to agree to disagree. The funny thing is I absolutely hope you’re right and I’m wrong. I just won’t base my future price and/or BO estimates on anything but a conservative measure. BTW, you are right in your assertion that many statin-eligible patients don’t take statins. A recent study concludes that only 50% of the eligible population takes statins. Just to stir the pot a little more, I’m going to assume that the take-up of V will be less than 50% as it is an added burden (cost, adherence) on top of statin use.