Amarin Corp Plc (AMRN)

[Sam81]

INDICATIONS AND USAGE------------------------------
VASCEPA is an ethyl ester of eicosapentaenoic acid (EPA) indicated:
• as an adjunct to maximally tolerated statin therapy to reduce the risk of myocardial infarction, stroke, coronary revascularization, and unstable
angina requiring hospitalization in adult patients with elevated triglyceride (TG) levels (≥ 150 mg/dL) and
o established cardiovascular disease or
o diabetes mellitus and 2 or more additional risk factors
for cardiovascular disease. (1)
• as an adjunct to diet to reduce TG levels in adult patients with severe
(≥ 500 mg/dL) hypertriglyceridemia. (1) Limitations of Use:
• The effect of VASCEPA on the risk for pancreatitis in patients with severe
hypertriglyceridemia has not been determined. (1)