Saturday, November 30, 2019 6:16:42 PM
I think that the Germans had a problem with the soc/control group from the moment they were involved in the trial.
I agree. I don't understand why she made that kind of statement.
Around 138 patients had their surgery more than 24 months before LL presentation.(see enrollment curve) The first group of 38 patients did not well. Only 13 patients of that group were still alive after 2 years and only 6 patients lived longer than 3 years and i assume that they were still alive at the time of her presentation. (there is evidence for that) Of the remaining 100 patients of the first group of 138, you can figure out that in the best case around 30-35 patients were still alive at the time of the presentation (Oct.2015)
200 patients were less than 2 years in the trial and half of them less than 1 year. IMO, you could not make any conclusion of that group at that time.
We have a lot of data (interim analysis 2017 and SNO 2018) and i still don't understand why she said in Oct.2015 that it seemed that everybody was living longer.
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