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Re: Mkc12five post# 9570

Monday, 11/25/2019 2:47:22 PM

Monday, November 25, 2019 2:47:22 PM

Post# of 17488
Roche is not the SoC right now, and the main advantage of VCS over Roche is that VCS has much a rapid response than Roche. this is more important than a CR at 78 weeks. for comparison we had a much higher delta vs placebo at 24 weeks than Roche. see attached details of Roche study. start page 18

https://www.roche.com/dam/jcr:656bf1a5-768c-4d91-a3db-b7440c3d6e7a/en/irp20191112.pdf

also we still don't have VCS long term results so we can still beat Roche numbers at 78 weeks. but the main thing is the rapidity of the response, and this is what made Neil comment that both drugs can be complementary and not competitve

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