NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

Jammy's point, I think, is that what really counts in this trial is the P value, not measure of degree of separation. The P value is the same regardless of using median, H/R or landmark as the effect measure.

The P value is presumably log rank. This does not assume any sort of proportional hazard. [I assume "bog standard K/M" was a typo]. The K/M curve itself is the basic starting point for every stat that has been discussed.

A single number, be it median, H/R or 36 month is a rough measure of the degree of separation. But hardly matters as if the P value is stat sig, then the curves will virtually certainly separate sufficiently to show a clear benefit.

I agree that curves are virtually never shown on initial top line, as that is held for the paper/meeting. I would say
this PR from SGEN is fairly typical. Shows the PFS/OS HR, Ci and P values along with a subgroup that I assume was consider key.