Anavex Life Sciences Corp (AVXL)

[TempePhil]

Doc and Anders see my post Comparing Rett Trofinetide results to Anavex results.
My post shows highlighted tables Doc references.

Note the Trofinetide trial was with 82 participants, and placebo controlled. The first 14 days (D14) obtained baseline data, and the full study was for 54 days (D54). The Anavex study was 6 patients, no placebo.

The 200mg/kg dose arm shows Trofinetide RSBQ score dropping 6.7, while the placebo arm drops 2.3.

Comparing these to the Anavex scores that dropped 16 points, we can see:
1) A2-73 provided a much stronger signal, >2x that of Trofinetide!
2) The placebo affect accounts for a drop of only 2.3 points. Assuming similar placebo affect with A2-73, there is still a very strong signal, two times as strong as Trofinetide!