Anavex Life Sciences Corp (AVXL)

[TempePhil]

Comparison of A273 and Trofinetide Results...

Comparing Trofinetide data to the Anavex data, we can see:
1) A2-73 provided a much stronger signal(16pts), >2x that of Trofinetide(6.7)!
2) The placebo affect accounts for a drop of only 2.3 points. Assuming similar placebo affect with A2-73, then A2-73 still has a very strong signal (still almost 2x better)!

This Trofinetide data is from your (and Steady's) link.
https://n.neurology.org/content/92/16/e1912

Here is the table of interest:


(Note: to view this table in the article...view pop up, at bottom left then select table 3 of 3.)

Caveat: The Trofinetide study had 82 patients with a placebo arm. The A2-73 study had 6 with no placebo.