Amarin Corp Plc (AMRN)

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sts - It's not very complicated. ALL of the below meet inclusion criteria WITHOUT needing a MACE in the secondary prevention cohort.

Secondary Prevention:

Defined as men and women ≥45 years of age with one or more of the following:

1. Documented coronary artery disease (CAD; one or more of the following primary criteria must be satisfied):

• Documented multi vessel CAD (≥50% stenosis in at least two major epicardial
coronary arteries – with or without antecedent revascularization);


2.
• Symptomatic carotid artery disease with ≥50% carotid arterial stenosis;
• Asymptomatic carotid artery disease with ≥70% carotid arterial stenosis per
angiography or duplex ultrasound;


3. Documented peripheral arterial disease (PAD; one or more of the following primary criteria must be satisfied):
• Ankle-brachial index (ABI) <0.9 with symptoms of intermittent claudication;
• History of aorto-iliac or peripheral arterial intervention (catheter-based or
surgical).

So there are likely many people in the secondary prevention group who never had a MACE in the RI study.