Amarin Corp Plc (AMRN)

[Atom0aks]

Here's what the trial design paper says about "established CVD" and prior events - I'll let you docs discuss whether this means "you've had an event" or not, but appears to me answer is yes - note the patient must have two or more conditions to be in risk stratum 1 (secondary prevention)...

The short answer is no, you can have established CVD without MACE. MACE is an outcome of CVD and there are several modalities available (e.g. imaging, ECG, markers, etc.) to evaluate your risk for CVD. Here is a brief list of some of the factors your doctor may look at to estimate your risk for CVD:

https://www.uptodate.com/contents/overview-of-possible-risk-factors-for-cardiovascular-disease#H10122097