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Re: AVII77 post# 208014

Monday, 08/12/2019 5:20:12 PM

Monday, August 12, 2019 5:20:12 PM

Post# of 425849
Thank you. Always enjoy your insight.

What are your thoughts about the following.

In the trial all patients are treated for LDL-C goal. So if mineral oil reduced absorption in same patients as soon as doctors saw LDL-C rising then they should have increased their statin dose canceling out any mineral oil effect.

Additionally, At the end even if LDL- C went up in the placebo a few points all patients in the placebo arm on average remained below the optimal level of LDL-C (100 mg/dl) so I just cannot see how mineral oil could explain the 25% reduction regardless of how you cut this pie.
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