CV Sciences Inc (CVSI)

[Deetew]

CLICK TO SEE FDA FRAUD IN REGARDS TO CBD

I was trained to detect fraud. I found fraud at the FDA. Let me point it out below:

Source:
7/25/19 Dr. Amy Abernathy Testimony on CBD

During our review of the marketing application for Epidiolex, we identified certain safety risks, including the potential for liver injury. In that context, the risks are outweighed by the benefits of the approved drug to the particular population for which it was intended.

--Dr. Amy Abernathy

As this issue progresses, we are committed to being transparent with the public about our path forward and providing information that is based on sound science and data.

--Dr. Amy Abernathy

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Source:
That Alarming CBD Liver Damage Study Is Bunk—And the Media Should Know Better by Leafly

The breathless reporting in Forbes focuses on a single, flawed, preclinical study and exaggerates it to the point of falsehood… A close examination of the Molecules study reveals a Pandora’s box of strange statements, problematic publishing, and unreasonable experimental design. On the first page, the abstract makes a claim that is fundamentally impossible, stating that, with chronic administration of CBD, ‘75% of mice gavaged with 615 mg/kg developed a moribund condition.’ But there were only 6 animals that received this dose! One doesn’t need an advanced degree in science or math to recognize that something is amiss. Seventy-five percent of six equals 4.5.

Dead mice aside (or rather, dead half-mice), the biggest problem with the study, according to Project CBD, is that just like in the 1974 rhesus monkey study, the dosage administered was astronomically high.

Scientists force-fed mice a single dose of CBD, ranging from the supposedly ‘low’ dosage of 246 mg/kg up to a mega-dose of 2460 mg/kg CBD… The maximum human dosage recommended for the CBD-isolate Epidiolex is 20 mg/kg, which is over 100x less than what the Little Rock researchers force fed their experimental mice.

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Source: Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy

Acute alcohol drinking induces steatosis, and effective prevention of steatosis can protect liver from progressive damage caused by alcohol. Increased oxidative stress has been reported as one mechanism underlying alcohol-induced steatosis. We evaluated whether cannabidiol, which has been reported to function as an antioxidant, can protect the liver from alcohol-generated oxidative stress-induced steatosis. Cannabidiol can prevent acute alcohol-induced liver steatosis in mice, possibly by preventing the increase in oxidative stress and the activation of the JNK MAPK pathway. Cannabidiol per se can increase autophagy both in CYP2E1-expressing HepG2 cells and in mouse liver. Importantly, cannabidiol can prevent the decrease in autophagy induced by alcohol. In conclusion, these results show that cannabidiol protects mouse liver from acute alcohol-induced steatosis through multiple mechanisms including attenuation of alcohol-mediated oxidative stress, prevention of JNK MAPK activation, and increasing autophagy.

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Conclusion:
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Dr. Amy Abernathy claims that the FDA is looking towards sound science in regards to CBD, but I'm sensing a bias in favor of big pharma based on the information above. I honestly believe that Dr. Amy Abernathy is part of a conspiracy to scare the public with bunk CBD science (much like 1974-marijuana science, Tobacco science, DDT science, and Fluoride science) so that the British GW Pharmaceuticals can prevail over all. The fact that she claims that the FDA is looking to sound science while citing a heavily discredited GW Pharmaceuticals study is concerning, and I think a governmental internal investigation should be opened against the FDA and their revolving door connections to big pharma. Sound the alarm now. Although I feel that dietary supplements will gain a legitimate pathway with CVSI being at the forefront of the pack, I feel that there is shady stuff going on at the FDA. We know a lot about the cannabis plant through research done by Israel, and they are not parroting the same concerns about the liver. This is reefer madness 2.0; this is your warning; stand up for your rights.

PS

Is the FDA in Britain's pocket or something? Why isn't she being more supportive of American farmers and businesses while giving all the praise in the world to GW Pharma? --A company that successfully got CBD derived from marijuana--not hemp--approved before any American had a chance to since it was and is still federally illegal, but as soon as a British Pharmaceutical company asks the FDA to approve their marijuana-based drug, the federal FDA approves the drug. Meanwhile, marijuana is still a schedule I drug with supposedly no approved medical uses. I'm calling you out you FDA frauds.

Here I was thinking that Trump was a protectionist. I guess I was wrong. The FDA reflects bad on you Trump.