Marker Therapeutics Inc (MRKR)

[poods]

I think one thing to keep in mind is we are seeing the responses (including a CR) with a relative low dose of cells (in the 10 million range). CAR-T are given in a 1-2 (and even 3)orders of magnitude greater dosing. They talked about increasing the dose and giving more doses, which makes obvious sense. You normally push a P1 until you see toxicity. We have seen no toxicity but we are seeing responses, so push the dose .
Simple axiom: If a little is good, more is better (until you get prohibitive toxicity).