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Re: Phantom Lord post# 27760

Tuesday, 07/23/2019 4:01:56 PM

Tuesday, July 23, 2019 4:01:56 PM

Post# of 34624
Great post and spot on. I count 8 more shots at a CR in arm A. 3 in already dosed patients and 5 in those yet to be dosed. If we were to see one more CR, I don't really think you could have equipoise for a randomized trial. IMO it would be unethical to give chemo without Multi-TAA. FDA many not agree or they may grant conditional approval and then track further CRs, while we enhance the pep mix. Not certain how this will go but another CR in arm A (or B) and MRKR will almost certainly get approval IMO. That can't be by chance.
If i had pancreatic Ca, right now I would beg borrow or steal to get Multi-TAA cells and I would not want to wait the 3 mo to see if I was responding to chemo. Give them as close to out of the gate as you can deliver them, I say. Best chance of success IMO.
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