Anavex Life Sciences Corp (AVXL)

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THIS WEEKS NEWS IS GOOD NEWS. AVXL 2-73 MAY INFLUENCE THE BODY TO CURE ITSELF AS HAS BEEN THE HYPOTHESIS ALL ALONG.

Mind-body connection:

"For example, neurological pathways connect parts of the brain that process emotions with the spinal cord, muscles, cardiovascular system, and digestive tract. This allows major life events, stressors, or emotions to trigger physical symptoms. You may have experienced this aspect of the mind-body connection when you feel butterflies in your stomach when you feel nervous, or when you heart feels like it is pounding out of your chest when you are under intense stress.

These intersecting systems help to establish the mind-body connection that influences the maintenance of health or the development of disease. For example, emotions like anxiety can trigger increased stress hormones, which may suppress the immune system and set the stage for the development of infections or cancer."

https://chopra.com/articles/mind-body-connection-understanding-the-psycho-emotional-roots-of-disease

The Brain Mind Body Connection with Dr. Rudy Tanzi

https://www.pbs.org/video/brain-mind-body-connection-dr-rudy-tanzi-wsvlfg/

''The Alzheimer’s disease puzzle Part 2: Clues from the microbiome
July 16, 2018
|
Madeline West & Dr Amy Loughman
In the previous article, we discussed limitations of current drug treatment approaches for Alzheimer’s disease (AD) and the growing understanding about the importance of lifestyle and health behaviours. This is where the gut microbiome comes in.

How could the microbiome be involved?
The bidirectional communication that takes place between the gut microbiota and the central nervous system has been coined the now popular term “gut-brain axis” that we write about here often. Our knowledge of this phenomenon has increased rapidly over recent years with the gut now associated with mental health and neurological conditions including depression, Parkinson’s disease, Huntington’s disease, and autism spectrum disorders. A small but convincing body of research also suggests a critical role of the microbiome in AD. Animal studies have shown that the microbiome and its metabolites play a causal role in AD by modulating blood-brain barrier permeability and amyloid levels. Additionally, preliminary data also show microbiome differences in people with early AD. ''

https://www.mindbodymicrobiome.com/single-post/2018/07/17/The-Alzheimer%E2%80%99s-disease-puzzle-Part-2-Clues-from-the-microbiome

Think Twice: How the Gut's "Second Brain" Influences Mood and Well-Being
The emerging and surprising view of how the enteric nervous system in our bellies goes far beyond just processing the food we eat

https://www.scientificamerican.com/article/gut-second-brain/

Anavex Life Sciences Presents New Clinical Data Identifying Gut Microbiota Biomarkers Associated with Improved Clinical Responses:

''The analysis was conducted using Ariana Pharma’s KEM® Artificial Intelligence, an FDA-tested technology to systematically explore combinations of biomarkers. Results revealed that patients treated with ANAVEX®2-73 had high levels of two gut microbiota families, Ruminococcaceae and Porphyromonadaceae, which were associated with improved activities of daily living (ADCS-ADL) at week 148 (p<0.01 and p<0.04, respectively).

Communication between gut microbiota and the brain has been shown to be a critical requirement of a healthy brain function. The reduction in gut microbiota diversity has become one of the hallmarks of aging, and disturbances in its composition are associated with several age-related neurological conditions, including Alzheimer’s disease. These changes in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neural injury, and ultimately neurodegeneration.4

Numerous pre-clinical studies demonstrate beneficial effects of SIGMAR1 (S1R) agonists on neuroinflammation, including with ANAVEX®2-735. The effect might potentially be reversal of the microbiota imbalances and might have a homeostatic effect on the brain-gut-microbiota axis.''

Anavex Life Sciences Presents New Clinical Data Identifying Gut Microbiota Biomarkers Associated with Improved Clinical Response...

https://www.globenewswire.com/news-release/2019/07/17/1884144/0/en/Anavex-Life-Sciences-Presents-New-Clinical-Data-Identifying-Gut-Microbiota-Biomarkers-Associated-with-Improved-Clinical-Response-in-Patients-Treated-with-ANAVEX-2-73-at-2019-Alzhei.html

CHECK OUT THE MIND BODY CONNECTION AND SPECIFICALLY THE GUT'S CONNECTION WITH THE BRAIN. IT IS EASY RESEARCH FOR ANYONE THAT DESIRES TO LEARN. YOU CAN EASILY FIND NUMEROUS REFERENCES RELATED TO THIS SUBJECT.