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Wednesday, 07/17/2019 11:30:48 AM

Wednesday, July 17, 2019 11:30:48 AM

Post# of 426507
Medscape article. Confusing (to me anyway!) as it seemingly endorses DHA, OTC etc. in addition to EPA yet it references MESA study & REDUCE IT which studied EPA.

https://www.medscape.com/viewarticle/915674

MESA: http://heartfailure.onlinejacc.org/content/early/2019/07/03/j.jchf.2019.03.008?download=true

Higher plasma EPA was significantly associated with reduced risk for HF, with both reduced and preserved EF. (Multi-Ethnic Study of Atherosclerosis [MESA]; NCT00005487)

In comments a doctor states:

Dr. Michael Mogadam 1 hour ago

This is a terrific informative study that re-affirms the cardio-protective role of long chain omega-3 PUFA. Most of the previous studies that found no CV benefits have been with low doses of about 1 gram omega-3. Other studies that measured blood levels or adipose tissue levels (on biopsy specimens) have shown that higher levels of omega-3 (both EPA and DHA) are cardio-protective.

So this study with detailed reporting of blood levels of EPA and DHA provides another rational basis to support the use of adequate doses (more than two grams per day) of omega-3PUFA. Since this would require eating several dark flesh (fatty) fish meals per week (salmon, tuna, ..), it would be quite impractical for most populations, hence we should consider very inexpensive over the counter (NOT PRESCRIPTION version) fish oil capsules.

Not all OTC fish oil capsules have adequate omega-3 PUFA or purification. For years I have recommended Nature's Bounty Fish Oil capsules, each having1400 mg total fish oil of which 647 mg is EPA and 253 mg DHA for a total of 980 mg omega-3. In the US at Costco a bottle of 130 odor-less coated softgel capsules sells for <$15, more than 10 times cheaper than the prescription version.

Seems he writes books:
https://www.amazon.com/Healthy-Breakthrough-Program-Prevent-Reverse/dp/0887235174/ref=sr_1_5?keywords=Michael+Mogadam&qid=1563377323&s=gateway&sr=8-5

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