Amarin Corp Plc (AMRN)

[MedResCollab]

Biobillionaire,

What is "cardiovascular IP"? How does one patent the CV system?

The extrapolated increase in EPA blood levels with a common Nordic Naturals (always rTG) dietary supplement of 1 g/d was 232% here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085663/

Notice also that even though the rTG form contained less EPA (650 mg) per tab than the ethyl ester form (753 mg), the resultant EPA increase from taken either was similar. Importantly, subjects consumed a well-controlled high fat diet during the study, and always took the supplements with food, which greatly helped the absorption of the EE form supplements. Something that does not happen in the real world, where polypharmacy is common before sleeping.

So, biobillionaire, what do you think would happen if subjects took just two of those Nordic Natural rTG form tabs (half the REDUCE-IT dose)? Would their EPA levels go up to the median seen in REDUCE-IT or higher? Yes, likely.