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georgejjl

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georgejjl

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Sunday, 06/02/2019 1:58:00 PM

Sunday, June 02, 2019 1:58:00 PM

Post# of 469766
Anavex 3-71 (formerly known as AF710b) is orders of magnitude (powers of 10) more potent

In addition, AF710B application altered the neurochemical profile to a state typified by downstream signaling of M1 mAChR and/or s1R. This was detected at concentrations in the nM range ~3–4 orders of magnitude lower than effects on other screened GPCRs, ion channels and transporters mentioned above (detailed data not shown, Table 1).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803577/

Good luck and GOD bless,

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