NorthWest Biotherapeutics Inc (NWBO)

[survivor1x]

Welcome to the board.

Can you tell me your thoughts on this and pspd vs. Pd differentiation?

https://www.pnas.org/content/114/38/10220

The case studies of the first three patients are outlined below. Patient A received tumor lysate-pulsed DCVax before imaging and then PD-1 antibody blockade during the interval between the first and second [18F]-CFA PET scans. The posttreatment [18F]-CFA PET scan demonstrated elevated uptake in several peripheral lymph nodes and in the tumor (Fig. 5A) compared with the first scan done 3 wk earlier, in agreement with the results of the murine studies. Advanced MRI revealed an increase in the tumor’s subtraction map (T1+C – T1). MRI with apparent diffusion coefficient (ADC) maps and cerebral blood volume (CBV) perfusion-weighted MRI suggested an almost 300% increase in immune cells in the tumor microenvironment, with the tumor volume remaining fairly constant (Fig. 6A).