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Re: abeta post# 227918

Saturday, 05/18/2019 7:30:35 PM

Saturday, May 18, 2019 7:30:35 PM

Post# of 688888
Abeta,

In 2012 the trial size had been increased up to 312 patients from previous 240 patients.

IMO the 24 UK patients are included in the 240 early patients.(see date Ethics Committee Opinion 2011-10-5 = Oct 5, 2011)

At that moment: E.8.6.3 specify the regions in which trial sites are planned: Germany, United Kingdom and United States.

So: 240-24= 216 planned to be included in United States.
24 in the UK.
87 in Germany.
remaining 21 of 348 patients planned ( IMO decision made between second half of 2012 and beginning of 2013???) to be included in Canada IMO.
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