NorthWest Biotherapeutics Inc (NWBO)

[iwasadiver]

It’s because everyone was in the same damn boat; trying to shove traditional models of “scorched earth” style drugs into the new realm of increasingly novel targeted therapies. Of course if you’re big pharma people will just assume you know what you’re doing and forgive a normal learning experience instead of vilifying you.

Ironically, and something that’s never been missed by people like yourself, Flipper, etc., Dr’s. Liau, Bosch, and Prins, along with NWBO (Including a very well versed on the subject matter Linda Powers) have steadily and quietly become, I believe, masters of the technology and of the trial science. Instead of folding they’ve persevered and I feel are actually driving some of the perceptions in the scientific community regarding how to figure out the precise methods to prove efficacy In a very complex and diverse disease. Non proportional Hazard Ratios are problematic when using traditional statistical analysis as a delay in treatment effect can confound what the reality may actually be. Using all the data one can to create supplemental measures of absolute benefit, I believe, is what NWBO is up to in their SAP.