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Re: McMagyar post# 182009

Saturday, 02/16/2019 7:43:10 PM

Saturday, February 16, 2019 7:43:10 PM

Post# of 462158
On the topic of the Michael J. Fox Foundation, I've been wondering about their continued commitment to the development of 2-73, since there hasn't really been further mention of their involvement beyond the pre-clinical funding which Anavex continues to tout in each press release. We do know, though, that the MJFF has been listed as a "partner" on Anavex's pddtrial.com recruitment website, but that in itself doesn't provide much further clarity.

Amidst the ludicrous discussions about Dr. Missling's physical appearance in the recent Bio CEO & Investor Conference interview, one thing I haven’t seen discussed is that Missling make mention here of further coordination with the MJFF. To my knowledge, his statement that the MJFF was involved in the decision to focus the Phase 2 trial on Parkinson’s Disease Dementia is the first substantive acknowledgement of a continuation of this partnership beyond the pre-clinical funding.

Full quote starting at about the 1:06 mark :

So we’ve been fortunate, the MJFF funded the entire preclinical studies for Parkinson’s Disease and the data was very promising. And then in combination with the foundation, we decided based on the cognitive data from the Phase 2A Alzheimer’s clinical study that the best way forward would be to combine the cognitive domain element as well as the motor impairment benefit, so that led to the design of the Parkinson’s Disease Dementia, or as we call it PDD, study.


I wonder if/when we hear more.
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