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Re: None

Thursday, 02/07/2019 7:24:53 AM

Thursday, February 07, 2019 7:24:53 AM

Post# of 698798
Optune OS and PFS at 24 months.

Because Optune stopped collecting data at 24 months post last patient enrolled, let's look at what happened there.

2 year OS Optune arm = 37% were left alive. (His KM graph though predicts 43%) The discrepancy is likely due to a massive number of censors.
2 year OS SOC arm = 26% were left alive. (His KM graph though predicts 31%) The discrepancy is likely due to a massive number of censors.

2 year PFS Optune arm = only 6% had not progressed.
2 year PFS SOC arm= only 4% had not progressed.
Virtually identical by two years.
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By comparison, combining the DCVax-L and SOC arms, because they are still blinded:

2 year OS SOC arm blended with DCVax-L arm = 45% were left alive. (KM graph though predicts 46%) The slight discrepancy is likely due to a small number of censors.



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