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Re: CogDiss 1188X post# 213073

Wednesday, 02/06/2019 2:09:02 AM

Wednesday, February 06, 2019 2:09:02 AM

Post# of 698785
"If p <= 0.05 is statistical nirvana then Merck may be on its way to roughly 45 successes, purely by chance."

One would hope the FDA and other equivalent bodies would take the multiplicity inherent at this scale into account when judging approval. i.e the first in class trial has a lower bar to pass (say p<0.05) but for each subsequent combination the bar gets higher.
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