NorthWest Biotherapeutics Inc (NWBO): But survival data is gonna be undeniabl...

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Re: photonic5 post# 211450

Friday, 02/01/2019 3:00:53 PM

Friday, February 01, 2019 3:00:53 PM

But survival data is gonna be undeniable.

If so, why has Les put crossover in play as an issue with getting results?

Undeniable OS results would be ITT treatment arm vs placebo arm, regardless of crossover. Many trials have crossover, they report the data as randomized and the crossover effect is not more or less than all the other OS confoundments caused by various follow-up treatments.

So why is this an issue here? Perhaps the OS arms do not separate and Les want to start laying the groundwork for crossover being the issue? If so, the data will certainly be "deniable".

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