Thursday, January 24, 2019 12:07:15 PM
You are mistaken We are talking about 2015 when LP had stated an efficacy IA would be performed and subsequently they have never mentioned it.
You are confusion this with 2014 when they said and efficacy IA would be performed then was slow to come clean that the trial had been enlarged and would take longer.
Also, a futility analysis (if done) would be part of the efficacy IA, and uses unblinded data.
Also, this "preserve the integrity of the trial" excuse is now off the table. The trial is over other than OS phone follow-up. There is no place left for bias to be introduced.
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