Cel Sci Corporation (CVM)

[Fosco1]

CIZ is in test group only (CIZ + LI), SOC arm and third arm don't have CIZ. Cyclophosphamide : this chemo is not boosting the immune system, on the contrary it inhibites cells replication. Tumor reduction has been noticed with Cyclophosphamide, but not as much as in this ph II trial with LI (42% response rate 30% to total tumor reduction). Thus the idea of the combination is to first paralize the enemy (injection of Cyclophosphamide 3 days prior LI) and then attack him by boosting defence cells with LI.
Ain't no oncologist but that's my understand for what's worth for
Take care
Fosco