Wednesday, January 23, 2019 2:38:39 PM
And from what I understand from reading, CIZ is not chemotherapy, it is extra immune boosting which is thought to help Multikine work more effectively?
Page 4
http://www.annualreports.com/HostedData/AnnualReports/PDF/AMEX_CVM_2017.pdf
"The primary endpoint for the protocol for this Phase 3 head and neck cancer study required that a 10% increase in overall survival be obtained in the
Multikine group which also is administered CIZ (CIZ = low dose (non-chemotherapeutic) of cyclophosphamide, indomethacin and Zinc-multivitamins) all of which
are thought to enhance Multikine activity), plus Standard of Care (Surgery + Radiotherapy or Chemoradiotherapy) arm of the study over the Control comparator
(Standard of Care alone) arm. As the study was designed, the final determination of whether this endpoint had been successfully reached could only be
determined when 298 events (deaths) had occurred in the combined comparator arms of the study."
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